| S.No. | Intermediate name | Cas No. | API |
|---|---|---|---|
| 1 | tert-Butyl 4-(5-(4-fluorobenzoyl)pyrimidin-2-yl)piperazine-1-carboxylate | 1703794-73-3 | Avapritinib |
| 2 | (4-fluorophenyl) (2-(piperazin-1-yl)pyrimidin-5-yl)methanone hydrochloride | 1703795-52-1 | Avapritinib |
| 3 | 6-broMopyrrolo [1,2-f] [1,2,4]triazin-(3H)-one | 888721-83-3 | Avapritinib |
| 4 | 4-chloro-6-(1-methyl-1H-pyrazol-4-yl)pyrrolo[2,1-f][1,2,4] triazine | 1703794-33-5 | Avapritinib |
| 5 | 5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine | 1180132-17-5 | Abemaciclib |
| 6 | 6-Bromo-4fluoro--1-isopropyl-2-methyl-1H-benzo[d]imidazole | 1231930-33-8 | Abemaciclib |
| 7 | 2,4-Dichloro-5-fluoropyrimidine | 2927-71-1 | Abemaciclib |
| 8 | (R)-3-Hydroxypyrrolidine | 2799-21-5 | Asciminib |
| 9 | 5-Bromo-6-chloronicotinic acid | 29241-62-1 | Asciminib |
| 10 | 1-(Tetrahydropyran-2-yl)-1H-pyrazole-5-boronic acid pinacol ester | 903550-26-5 | Asciminib |
| 11 | 4-(Chloro-difluoro-methoxy)-phenylamine | 39065-95-7 | Asciminib |
| 12 | 1375541-21-1 | Atogepant | |
| 13 | 1456803-43-2 | Atogepant | |
| 14 | 4-Methyl-2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine | 1378865-93-0 | Alpelisib |
| 15 | 1-Bromo-8-chloronaphthalene | 20816-79-9 | Adagrasib |
| 16 | tert-Butyl 2,4-dichloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine-7-carboxylate | 916420-27-4 | Adagrasib |
| 17 | 2-Propenoic acid, 2-fluoro-,sodium sal | 74893-46-2 | Adagrasib |
| 18 | (R)-1-Boc-3-hydroxymethylpiperazine | 278788-66-2 | Adagrasib |
| 19 | 1672665-55-2 | Belzutifan | |
| 20 | 1672665-29-0 | Belzutifan | |
| 21 | 1672668-41-5 | Belzutifan | |
| 22 | 2738675-96-0 | Belzutifan | |
| 23 | 2bromo--N-isopropylacetamide | 75726-96-4 | Belumosudil |
| 24 | 1-Boc-5-aminoindazole | 129488-10-4 | Belumosudil |
| 25 | Phenol, 3-(4-chloro-2-quinazolinyl)-,1-acetate | 911417-24-8 | Belumosudil |
| 26 | N-2: | 911417-26-0 | Belumosudil |
| 27 | (S)-3-Amino-3-(4-chlorophenyl)propan-1-ol | 886061-26-3 | Capivasertib |
| 28 | N-boc-amino-piperidinyl-1,1-carboxylic acid | 252720-31-3 | Capivasertib |
| 29 | 7-(Benzyloxy)-3-bromo-1,2-dihydronaphthalene | 722536-73-4 | Elacestrant |
| 30 | N-(2-bromo-5-methoxyphenyl)acetamide | 123027-99-6 | Elacestrant |
| 31 | N-ethyl-4formyl--Benzeneacetamide | 2477812-42-1 | Elacestrant |
| 32 | 4-Fluoro-2-methylphenylboronic acid | 139911-29-8 | Elinzanetant |
| 33 | 2-(3,5-bis(trifluoro Methyl)phenyl)-2-Methyl propanoic acid | 289686-70-0 | Elinzanetant |
| 34 | (7S,9AS)-Octahydropyrazino [2,1-C] [1,4] Oxazine-7-methanol hcl | Elinzanetant | |
| 35 | 4-Amino-5-methyl-2(1H)-pyridinone | 95306-64-2 | Finerenone |
| 36 | 2-Methoxy-4-cyanobenzaldehyde | 21962-45-8 | Finerenone |
| 37 | (Z)-2-cyanoethyl 2-(4-cyano-2-methoxybenzylidene)-3-oxobutanoate | 1050477-39-8 | Finerenone |
| 38 | (R)-3-methyl-2-ketopiperazine | 922178-61-8 | Fezolinetant |
| 39 | 3-Methyl-1,2,4-thiadiazole-5-carbohydrazide | 1375066-73-1 | Fezolinetant |
| 40 | 3-Methyl-[1,2,4]thiadiazole-5-carboxylic acid ethyl ester | 76162-56-6 | Fezolinetant |
| 41 | 1902955-29-6 | Fexuprazan | |
| 42 | 701-27-9 | Fexuprazan | |
| 43 | 2408761-20-4 | Iptacopan | |
| 44 | 1481631-51-9 | Iptacopan | |
| 45 | 1644667-61-7 | Iptacopan | |
| 46 | 2408761-21-5 | Iptacopan | |
| 47 | 2189684-53-3 | Lenacapavir | |
| 48 | 1620056-83-8 | Lenacapavir | |
| 49 | 2189684-54-4 | Lenacapavir | |
| 50 | 1620056-47-4 | Lenacapavir | |
| 51 | 2109226-54-0 | Lenacapavir | |
| 52 | 2375019-75-1 | Lenacapavir | |
| 53 | 3-Phenyl-1H-Pyrazole-4-Carbaldehyde | 26033-20-5 | Lazertininb |
| 54 | 4-fluoro-2-Methoxy-5-nitroaniline | 1075705-01-9 | Lazertininb |
| 55 | 1903009-56-2 | Lazertininb | |
| 56 | 3-Ethyl bicyclo[3.2.0]hept-3-en-6-one | 1235479-59-0 | Mirogabalin |
| 57 | (1R,5S)-3-ethylbicyclo[3.2.0]hept-3-en-6-one | 1235479-61-4 | Mirogabalin |
| 58 | 1,2,3,5-Tetra-O-Acetyl-Beta-L-Ribofuranose | 144490-03-9 | Maribavir |
| 59 | 2-Bromo-5,6-Dichlorobenzimidazole | 142356-40-9 | Maribavir |
| 60 | 4,5-Dichloro-1,2-benzenediamine | 5348-42-5 | Maribavir |
| 61 | 5-Bromo-4-fluoro-1-methyl-1H-indazole | 1784678-61-0 | Orforglipron |
| 62 | (S)-3-Aminobutanenitrile hydrochloride | 1073666-54-2 | Orforglipron |
| 63 | 2212021-61-7 | Orforglipron | |
| 64 | :2212021-83-3 | Orforglipron | |
| 65 | 769132-28-7 | Obicetrapib | |
| 66 | 952582-00-2 | Obicetrapib | |
| 67 | 952582-02-4 | Obicetrapib | |
| 66 | Tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate | 571188-59-5 | Palbociclib |
| 67 | 6-bromo-2-chloro-8-cyclopentyl-5-Methylpyrido [2,3-d]pyrimidin-7(8H)-one | 1016636-76 | Palbociclib |
| 68 | 7,8-Dihydro-5H-cyclohepta[b]pyridine-5,9(6H)-dione | 39713-40-1 | Rimegepant |
| 69 | 1190363-46-2 | Rimegepant | |
| 70 | 1373116-04-1 | Rimegepant | |
| 71 | 1,3-Dihydro-1-[1-(1H-imidazol-1-ylcarbonyl)-4-piperidinyl]-2H-imidazo [4,5-b]pyridin-2-one | 1373116-06-3 | Rimegepant |
| 72 | (1S)-2,2,2-trifluoro-1-methylethyl]hydrazine hydrochloride | 2764851-03-6 | Pirtobrutinib |
| 73 | Potassium trifluoro ((5-fluoro-2-methoxybenzamido)methyl)borate | 2089246-64-8 | Pirtobrutinib |
| 74 | 2-[(4-bromophenyl)methoxymethylene] Malononitrile | 1188083-45-5 | Pirtobrutinib |
| 75 | 107228-51-3 | Resmetirom | |
| 76 | 920509-27-9 | Resmetirom | |
| 77 | 920509-28-0 | Resmetirom | |
| 78 | 4/5/6629 | Resmetirom | |
| 79 | 1207853-23-3 | Ritlecitinib | |
| 80 | 90213-66-4 | Ritlecitinib | |
| 81 | 2042650-70-2 | Ritlecitinib | |
| 82 | 1792180-81-4 | Ritlecitinib | |
| 83 | (S)-2-((4-(Trifluoromethyl)phenoxy)methyl)oxirane | 256372-58-4 | Seladelpar |
| 84 | 2-(4-Mercapto-2-methylphenoxy)-acetic acid ethyl este | 343322-82-7 | Seladelpar |
| 85 | 4-Trifluoromethylphenol | 402-45-9 | Seladelpar |
| 86 | 1023742-13-3 | Selumetinib | |
| 87 | 606143-46-8 | Selumetinib | |
| 88 | 391212-29- | Selumetinib | |
| 89 | 2252403-82-8 | Sotorasib | |
| 90 | (S)-4-N-Boc-2-methylpiperazine | 147081-29-6 | Sotorasib |
| 91 | 2-Fluoro-6-methoxyphenylboronic acid | 78495-63-3 | Sotorasib |
| 92 | 1662688-20-1 | Semaglutide | |
| 93 | 1118767-16-0 | Semaglutide | |
| 94 | Sema peptide | 1169630-82-3 | Semaglutide |
| 95 | SNAC | 203787-91-1 | Semaglutide |
| 96 | 3-Amino-4,5-dimethylisoxazole | 13999-39-8 | Sparsentan |
| 97 | 415697-56-2 | Sparsentan | |
| 98 | R-5,7-Difluorochroman-4-ol | 1270294-05-7 | Tegoprazan |
| 99 | 4-Hydroxy-N,N,2-trimethyl-1-tosyl-1H-benzo[djimidazole-6-carboxamide | 942195-86-0 | Tegoprazan |
| 100 | 1-benzyl-4-hydroxy-2-methyl-1H-benzo[d]imidazole-6-carboxylic acid | 1640981-19-6 | Tegoprazan |
| 101 | Fmoc-L-Lys[C20-OtBu-Glu(OtBu)-AEEA-AEEA}-OH | 2460751-66-8 | Tirzepatide |
| 102 | 20-(tert-Butoxy)-20-oxoicosanoic acid | 683239-16-9 | Tirzepatide |
| 102 | :1095824-76-2 | Tovorafenib | |
| 103 | 1095824-77-3 | Tovorafenib | |
| 104 | 914916-98-6 | Tovorafenib | |
| 105 | 1-(1,1-Dimethylethyl)-1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one | 1455358-06-1 | Ubrogepant |
| 106 | 1375541-21-1 | Ubrogepant | |
| 107 | 1456803-37-4 | Ubrogepant | |
| 108 | (3R,4S)-3-(2-Bromoacetyl)-4-ethyl-1-pyrrolidinecarboxylic acid phenylmethyl ester | 1428243-26-8 | Upadacitinib |
| 109 | tert-butyl 5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-ylcarbamate | 1201187-44-1 | Upadacitinib |
| 110 | 2,2,2-Trifluoroethylamine hydrochloride | 373-88-6 | Upadacitinib |
| 111 | 3-Chloro-4-(pyridin-3-yl)-1,2,5-thiadiazole | 131986-28-2 | Xanomeline |
| 112 | Methyl (2R)-2-amino-3-(7-methyl-1H-indazol-5-yl)propanoate dihydrochloride | 1414976-14-9 | Zavegepant |
| 113 | 3-(Piperidin-4-yl)quinolin-2(1H)-one hydrochloride | 855778-84-6 | Zavegepant |
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